Buy Ipamorelin UK
Buy Ipamorelin UK. Selective growth hormone secretagogue for GH research. ≥99% purity. Fast UK delivery.
What is Ipamorelin?
Ipamorelin is a synthetic pentapeptide growth hormone secretagogue that selectively stimulates growth hormone (GH) release from pituitary somatotrope cells. Distinguished by its high selectivity, ipamorelin causes minimal effects on cortisol and prolactin levels, making it an invaluable research tool for studying isolated GH secretion mechanisms.
Developed as a ghrelin receptor (GHS-R) agonist, ipamorelin represents one of the most selective GH releasing peptides (GHRPs) available for research. Its clean pharmacological profile enables researchers to study GH axis physiology without the confounding effects seen with less selective compounds.
Peptide Shop supplies research-grade Ipamorelin with guaranteed ≥99% purity, verified through comprehensive HPLC and mass spectrometry analysis.
How Does Ipamorelin Work?
Ipamorelin activates growth hormone secretagogue receptors (GHS-R) in the anterior pituitary, triggering GH release through multiple mechanisms.
Receptor Activation
- GHS-R binding - High-affinity ghrelin receptor agonism
- Calcium signalling - Intracellular Ca²⁺ elevation in somatotropes
- cAMP pathway - Secondary signalling cascade activation
- GH exocytosis - Stimulated hormone granule release
Selectivity Profile
Ipamorelin’s research value lies in its selectivity:
- Minimal cortisol effects - Unlike GHRP-6
- Minimal prolactin effects - Clean hormonal profile
- No appetite stimulation - Unlike ghrelin itself
- Dose-dependent GH release - Predictable research tool
Synergy with GHRH
Research often combines ipamorelin with GHRH analogs:
- Complementary mechanisms - Different receptor targets
- Enhanced GH release - Synergistic effects
- CJC-1295 combinations - Popular research paradigm
Research Applications
Pituitary Function
- Somatotrope biology - GH-producing cell research
- GH secretion dynamics - Pulsatile release studies
- Receptor pharmacology - GHS-R characterisation
GH Axis Research
- IGF-1 pathways - Downstream signalling
- GH feedback - Regulatory mechanism studies
- Age-related changes - Somatopause research
Metabolic Studies
- Body composition - GH effects on tissues
- Lipid metabolism - Fat utilisation pathways
- Protein synthesis - Anabolic mechanism research
Ipamorelin Peptide Specifications
| Specification | Detail |
|---|---|
| CAS Number | 170851-70-4 |
| Molecular Formula | C38H49N9O5 |
| Molecular Weight | 711.9 g/mol |
| Sequence | Aib-His-D-2-Nal-D-Phe-Lys-NH₂ |
| Purity | ≥99% (HPLC) |
| Appearance | White lyophilised powder |
| Solubility | Freely soluble in water |
| Identity | Confirmed by mass spectrometry |
Storage and Handling
| Condition | Temperature | Duration |
|---|---|---|
| Lyophilised | -20°C | Up to 24 months |
| Reconstituted | 2-8°C | Up to 4 weeks |
| Frozen aliquots | -20°C | Up to 3 months |
Ordering Information
| Size | Recommended For |
|---|---|
| 2 mg | Pilot studies |
| 5 mg | Standard research |
Minimum order: £200 | 10% discount on orders over £200
Research Use Statement
For laboratory research only. Not intended for human or veterinary use.
Product Specifications
| CAS Number | 170851-70-4 |
|---|---|
| Molecular Weight | 711.9 g/mol |
| Purity | ≥ 99% |
| Storage | -20°C recommended (research-only) |
| Available Sizes | 10 × 5 mg vials |
| Price Range | £250 per pack |
FAQ
Ipamorelin is used to study growth hormone secretion, ghrelin receptor (GHS-R) activation, and somatotrope cell function. It's valued for its selectivity, causing minimal effects on cortisol and prolactin compared to other GHRPs.
Ipamorelin is highly selective for GH release with minimal effects on cortisol, prolactin, and appetite. This makes it valuable for studying isolated GH secretion mechanisms without confounding hormonal effects.
Ipamorelin acts as a ghrelin mimetic, binding to growth hormone secretagogue receptors (GHS-R) in the pituitary to stimulate GH release. It works synergistically with GHRH in research models.
Store lyophilised Ipamorelin at -20°C for long-term stability. Once reconstituted, keep at 2-8°C and use within 4 weeks. Avoid freeze-thaw cycles.
Our Ipamorelin is ≥99% pure as verified by HPLC. Each batch includes a Certificate of Analysis with purity data and mass spectrometry identity confirmation.
Yes, researchers often study ipamorelin combined with CJC-1295 to investigate GHRP-GHRH synergy. Both peptides are available from Peptide Shop.
Reconstitute in sterile bacteriostatic water. Add solvent slowly along the vial wall and gently swirl to dissolve. Ipamorelin dissolves readily in water.
Ipamorelin is available in 2mg and 5mg vials for various research scales.
Customer Reviews (18)
Based on 18 reviews
Dr. Michael Roberts • 2024-12-14Verified Purchase
Our pituitary function studies require selective GHRPs. Peptide Shop' Ipamorelin is perfect - high purity with minimal cortisol effects in our assays.
Cambridge Endocrine Lab • 2024-12-07Verified Purchase
Ipamorelin selectivity is crucial for our research. Quality from Peptide Shop is consistently excellent.
James Foster • 2024-11-30Verified Purchase
Fast delivery, excellent quality. GH release assays show expected results.
Edinburgh GH Studies • 2024-11-23Verified Purchase
Consistent quality for our secretagogue research. Peptide Shop is our preferred source.
Dr. Sarah Mitchell • 2024-11-16Verified Purchase
Verified purity exceeds claims. Essential for serious growth hormone research.
Manchester Hormone Lab • 2024-11-09Verified Purchase
Fast delivery, great quality. The selectivity profile is exactly what we need.
Sophie Williams • 2024-11-02Verified Purchase
Express delivery arrived next day. Product quality excellent.
Oxford Pituitary Research • 2024-10-26Verified Purchase
Quality is excellent. Would give 5 stars with a 10mg bulk option.
Dr. Robert Hayes • 2024-10-19Verified Purchase
Excellent for somatotrope studies. Quality and documentation meet our requirements.
Newcastle Endocrine Lab • 2024-10-12Verified Purchase
Multiple orders, consistently excellent. Essential for our GH secretion research.
Michael Thompson • 2024-10-05Verified Purchase
Easy ordering, quick delivery. Ipamorelin quality is exactly as described.
Glasgow Peptide Lab • 2024-09-28Verified Purchase
High-quality GHRP with proper documentation. Highly recommended.
Dr. Catherine Moore • 2024-09-21Verified Purchase
Research-grade quality for our somatotrope culture studies.
Bristol GH Research • 2024-09-14Verified Purchase
Premium ipamorelin for our GHRP-GHRH synergy studies.
Emma Richardson • 2024-09-07Verified Purchase
Quality peptide at a fair price. Essential for GH research.
Southampton Hormone Lab • 2024-08-31Verified Purchase
Our pituitary cell assays require pure peptides. Peptide Shop delivers.
Dr. Andrew Foster • 2024-08-24Verified Purchase
Outstanding quality for growth hormone secretion research.
Leeds Endocrine Studies • 2024-08-17Verified Purchase
Multiple orders, always excellent quality. Our preferred GHRP source.
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