Buy 5-Amino-1MQ
Buy 5-Amino-1MQ. Available as oral capsules (50mg) or high-purity powder (99%). NNMT inhibitor for metabolism and longevity research. Fast UK delivery.
What is 5-Amino-1MQ?
5-Amino-1MQ (5-Amino-1-Methylquinolinium) is a selective inhibitor of nicotinamide N-methyltransferase (NNMT), an enzyme increasingly recognised as a key regulator of cellular metabolism, NAD+ homeostasis, and adipose tissue function. This research compound has emerged as an important tool for studying the intersection of epigenetics, energy metabolism, and ageing.
NNMT catalyses the N-methylation of nicotinamide (a NAD+ precursor) using SAM (S-adenosylmethionine) as a methyl donor. By inhibiting this enzyme, 5-Amino-1MQ enables researchers to investigate how NNMT modulation affects cellular metabolism, NAD+ availability, and metabolic health.
Peptide Shop supplies research-grade 5-Amino-1MQ with guaranteed ≥99% purity, verified through comprehensive HPLC analysis.
How Does 5-Amino-1MQ Work?
5-Amino-1MQ inhibits NNMT, affecting multiple metabolic pathways:
NAD+ Metabolism
- Nicotinamide preservation - Less substrate consumed by NNMT
- NAD+ precursor availability - More nicotinamide for salvage pathway
- Cellular energy - Potential effects on mitochondrial function
- Sirtuin activity - NAD+-dependent deacetylase regulation
Methylation Balance
- SAM conservation - Reduced consumption by NNMT
- Methylation capacity - Effects on other methyltransferases
- Epigenetic regulation - Downstream effects on gene expression
Adipose Tissue
- NNMT is highly expressed in fat - Key research target
- Adipocyte metabolism - Effects on lipid handling
- Obesity research - Understanding NNMT’s role
Research Applications
Metabolic Research
- NAD+ biology - Understanding salvage pathway regulation
- Energy metabolism - Mitochondrial function studies
- Adipose function - Fat tissue metabolism
Longevity Research
- NAD+ and ageing - Cellular senescence studies
- Metabolic health - Age-related decline research
- Intervention targets - Therapeutic development
Obesity Studies
- Adipose NNMT - Fat tissue expression studies
- Metabolic dysfunction - Disease mechanism research
Specifications
| Specification | Detail |
|---|---|
| CAS Number | 42464-99-1 |
| Molecular Weight | 240.3 g/mol |
| Purity | ≥99% (HPLC) |
| Appearance | White to off-white powder |
| Solubility | Soluble in water, DMSO |
Storage
Store at room temperature, protected from light and moisture.
Ordering Information
| Size | Price |
|---|---|
| 100 mg | From £38 |
| 250 mg | From £85 |
Minimum order: £200 | 10% discount on orders over £200
Research Use Statement
For laboratory research only. Not intended for human or veterinary use.
Product Specifications
| CAS Number | 42464-99-1 |
|---|---|
| Molecular Weight | 240.3 g/mol |
| Purity | ≥ 99% |
| Storage | Room temperature, protected from light |
| Available Sizes | 30 caps |
| Price Range | £40 per bottle |
FAQ
We offer 5-Amino-1MQ in two convenient forms: Oral Capsules (50mg per capsule) for precise dosing convenience, and High-Purity Powder (99%) for flexible research applications. Both forms maintain the same exceptional purity standards.
5-Amino-1MQ is used to study nicotinamide N-methyltransferase (NNMT) inhibition and its effects on cellular metabolism, NAD+ levels, energy expenditure, and adipose tissue function. It's a key tool for metabolic ageing and obesity research.
NNMT is an enzyme that methylates nicotinamide, consuming SAM (S-adenosylmethionine). High NNMT activity is associated with obesity and metabolic dysfunction. Inhibition may preserve NAD+ precursors and improve metabolic function.
By inhibiting NNMT, 5-Amino-1MQ may preserve nicotinamide for NAD+ synthesis rather than methylation. This research application connects to NAD+ biology and cellular energy metabolism.
Store at room temperature, protected from light and moisture. Both capsule and powder forms are stable at ambient conditions when kept dry. Capsules should be kept in their original container.
Our 5-Amino-1MQ is ≥99% pure as verified by HPLC. Both capsule and powder forms meet this purity standard. Each batch includes a Certificate of Analysis with purity and identity data.
Oral Capsules (50mg) offer precise, pre-measured doses ideal for consistent research protocols. High-Purity Powder (99%) provides flexibility for custom concentration preparation and larger-scale studies.
A minimum purchase of £200 is required for 5-Amino-1MQ orders. This applies to any combination of capsules or powder forms.
Customer Reviews (12)
Based on 12 reviews
Dr. Helen Foster • 2024-12-10Verified Purchase
Our NNMT inhibition studies require high-purity compounds. Peptide Shop delivers excellent quality with thorough documentation.
Cambridge Metabolism Lab • 2024-12-03Verified Purchase
5-Amino-1MQ purity is exceptional. Essential for our adipose tissue research programme.
James Morrison • 2024-11-26Verified Purchase
Fast delivery, excellent quality. Perfect for our metabolic enzyme studies.
Edinburgh Ageing Research • 2024-11-19Verified Purchase
Consistent quality for our longevity studies. Peptide Shop has become our preferred supplier.
Dr. Robert Clarke • 2024-11-12Verified Purchase
Verified purity matches claims. Essential for serious NNMT research.
Manchester NAD+ Studies • 2024-11-05Verified Purchase
Fast delivery, great quality. The 250mg size is excellent value for larger studies.
Sophie Williams • 2024-10-29Verified Purchase
Express delivery was prompt. Product quality excellent for our enzyme inhibition research.
Oxford Adipose Research • 2024-10-22Verified Purchase
Quality is excellent. Minor feedback - would appreciate even larger bulk sizes.
Dr. Catherine Moore • 2024-10-15Verified Purchase
Excellent for studying NNMT's metabolic role. Quality meets our requirements.
Newcastle Metabolic Studies • 2024-10-08Verified Purchase
Multiple orders, consistently excellent. Essential for our NAD+ metabolism research.
Michael Thompson • 2024-10-01Verified Purchase
Easy ordering, quick delivery. 5-Amino-1MQ quality is exactly as described.
Glasgow Epigenetics Lab • 2024-09-24Verified Purchase
High-quality compound with proper documentation. Highly recommended for methylation research.
Related Products
View All Peptides
