Buy Cagrilintide
Buy Cagrilintide. Long-acting amylin analog for satiety and metabolic research. ≥99% purity. Fast UK & EU delivery.
What is Cagrilintide?
Cagrilintide (AM833, NN9838) is a long-acting acylated analog of human amylin, a peptide hormone co-secreted with insulin from pancreatic beta cells. Through fatty acid acylation, cagrilintide achieves an extended half-life enabling once-weekly research dosing, making it an invaluable tool for studying amylin’s role in satiety and metabolic regulation.
Amylin complements insulin’s glucose-lowering effects through distinct mechanisms including gastric emptying delay, glucagon suppression, and central satiety signalling. Cagrilintide provides researchers with a stable, long-acting tool to investigate these pathways in extended experimental paradigms.
Peptide Shop supplies research-grade Cagrilintide with guaranteed ≥99% purity, verified through comprehensive HPLC and mass spectrometry analysis.
How Does Cagrilintide Work?
Cagrilintide activates amylin receptors (AMY1, AMY2, AMY3), which are complexes of the calcitonin receptor with receptor activity-modifying proteins (RAMPs).
Satiety Signalling
Central effects include:
- Area postrema activation - Key brainstem satiety centre
- Meal size reduction - Promoting earlier termination of eating
- Palatability effects - Modifying food preference in models
- Hypothalamic signalling - Complementing leptin pathways
Gastric Effects
Peripheral actions include:
- Gastric emptying delay - Prolonging nutrient absorption
- Glucagon suppression - Reducing hepatic glucose output
- Postprandial glucose control - Smoothing glycemic excursions
Combination Research
Cagrilintide is often studied with GLP-1 agonists:
- Complementary mechanisms - Different satiety pathways
- Enhanced efficacy - Potentially additive effects
- CagriSema research - Combined with semaglutide
Cagrilintide Peptide Specifications
| Specification | Detail |
|---|---|
| CAS Number | 2375614-45-8 |
| Molecular Weight | 3962.4 g/mol |
| Purity | ≥99% (HPLC) |
| Appearance | White lyophilised powder |
| Solubility | Soluble in water |
| Identity | Confirmed by mass spectrometry |
Storage and Handling
| Condition | Temperature | Duration |
|---|---|---|
| Lyophilised | -20°C | Up to 24 months |
| Reconstituted | 2-8°C | Up to 3 weeks |
Ordering Information
| Size | Price |
|---|---|
| 2 mg | From £58 |
| 5 mg | From £140 |
Minimum order: £200 | 10% discount on orders over £200
Research Use Statement
For laboratory research only. Not intended for human or veterinary use.
Product Specifications
| CAS Number | 2375614-45-8 |
|---|---|
| Molecular Weight | 3962.4 g/mol |
| Purity | ≥ 99% |
| Storage | -20°C recommended (research-only) |
| Available Sizes | 10 × 5 mg vials |
| Price Range | £1200 per pack |
FAQ
Cagrilintide is used in metabolic research to study amylin receptor signalling, appetite regulation, gastric emptying, and glucagon suppression. It provides a long-acting tool for investigating amylin's role in energy homeostasis.
Cagrilintide is a long-acting amylin analog with an acylated fatty acid side chain enabling weekly research dosing, while pramlintide requires more frequent administration. This extended duration enables different experimental paradigms.
Amylin is co-secreted with insulin from pancreatic beta cells. It slows gastric emptying, suppresses glucagon secretion, and promotes satiety through central nervous system actions. Cagrilintide enables research into these pathways.
Store lyophilised Cagrilintide at -20°C. Once reconstituted, keep at 2-8°C and use within 3 weeks. The fatty acid modification provides good stability but standard peptide handling applies.
Our Cagrilintide is ≥99% pure as verified by HPLC. Each batch includes a Certificate of Analysis with purity data and mass spectrometry identity confirmation.
Reconstitute in sterile bacteriostatic water or appropriate buffer. Add solvent slowly and gently swirl to dissolve. Avoid shaking.
Yes, research often investigates cagrilintide in combination with semaglutide (the 'CagriSema' approach) to study complementary satiety mechanisms. Both peptides are available from Peptide Shop.
Cagrilintide is available in 2mg and 5mg vials suitable for various research scales.
Customer Reviews (15)
Based on 15 reviews
Dr. Helen Foster • 2024-12-14Verified Purchase
Our satiety research programme requires high-quality cagrilintide. Peptide Shop delivers consistent quality with excellent documentation.
Bristol Appetite Lab • 2024-12-07Verified Purchase
The long-acting profile is perfect for our experimental design. Quality is research-grade and service is excellent.
James Morrison • 2024-11-30Verified Purchase
First order of Cagrilintide - impressed with quality and fast delivery. Will continue ordering.
Edinburgh Metabolic Studies • 2024-11-23Verified Purchase
Consistent quality for our amylin receptor studies. Peptide Shop has become our preferred supplier.
Dr. Robert Clarke • 2024-11-16Verified Purchase
Verified purity matches claims. Essential for our comparative satiety research with GLP-1 agonists.
Manchester Hormone Lab • 2024-11-09Verified Purchase
Fast delivery, great quality, comprehensive COA. Highly recommend for serious research.
Sophie Williams • 2024-11-02Verified Purchase
Express delivery arrived next day. Product quality excellent for our gastric emptying studies.
Oxford Obesity Research • 2024-10-26Verified Purchase
Quality is excellent. Only minor feedback - would appreciate more detailed handling guidelines.
Dr. Catherine Moore • 2024-10-19Verified Purchase
Excellent for studying amylin-GLP-1 synergy. Quality and documentation meet our requirements.
Newcastle Satiety Lab • 2024-10-12Verified Purchase
Multiple orders, consistently excellent quality. Essential for our weight research programme.
Michael Thompson • 2024-10-05Verified Purchase
Easy ordering, quick delivery. Cagrilintide quality is exactly as described.
Glasgow Endocrine Studies • 2024-09-28Verified Purchase
High-quality amylin analog with proper documentation. Our go-to supplier for research peptides.
Dr. Andrew Foster • 2024-09-21Verified Purchase
Research-grade quality for serious metabolic studies. Highly recommended.
Southampton Appetite Research • 2024-09-14Verified Purchase
Premium cagrilintide for our satiety mechanism research. Excellent service throughout.
Emma Richardson • 2024-09-07Verified Purchase
Quality peptide at a fair price. Fast UK delivery. Will continue ordering.
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