Buy AOD-9604 UK
Buy AOD-9604 UK. Research grade GH fragment for fat metabolism studies. ≥99% purity. Fast UK delivery.
What is AOD-9604?
AOD-9604 (Anti-Obesity Drug 9604) is a modified fragment of human growth hormone comprising amino acids 177-191 of the C-terminal region, with an additional tyrosine residue at the N-terminus. This synthetic peptide was specifically designed to isolate the fat-metabolising properties of growth hormone without its growth-promoting or diabetogenic effects.
Originally developed by Metabolic Pharmaceuticals in Australia, AOD-9604 represents one of the most targeted approaches to studying growth hormone’s lipolytic activity. By using only the fat-reducing portion of the full hormone, researchers can investigate adipose tissue metabolism without confounding effects on IGF-1 or glucose homeostasis.
Peptide Shop supplies research-grade AOD-9604 with guaranteed ≥99% purity, verified through comprehensive HPLC and mass spectrometry analysis. Each order includes a detailed Certificate of Analysis, ensuring researchers receive properly characterised material for their studies.
How Does AOD-9604 Work?
AOD-9604’s mechanism of action centres on its ability to stimulate lipolysis and inhibit lipogenesis in adipose tissue, mimicking a specific subset of growth hormone’s metabolic effects.
Lipolytic Activity
The peptide promotes fat breakdown through:
- Beta-3 adrenergic receptor interaction - Research suggests enhancement of lipolytic signalling
- cAMP pathway activation - Increased intracellular signalling in adipocytes
- Hormone-sensitive lipase activation - Enhanced triglyceride breakdown
- Free fatty acid release - Mobilisation of stored fat for oxidation
Anti-Lipogenic Effects
AOD-9604 also inhibits fat accumulation:
- Reduced lipogenesis - Decreased conversion of glucose to stored fat
- Adipocyte differentiation effects - Research on fat cell maturation
- Metabolic enzyme modulation - Effects on key lipid synthesis pathways
Selective Action
A key research advantage is its selectivity:
- No IGF-1 elevation - Unlike full growth hormone
- No glucose effects - Preserved insulin sensitivity in research models
- No growth promotion - Isolated metabolic effects
- Targeted adipose action - Focus on fat tissue metabolism
Research Applications of AOD-9604
Fat Metabolism Studies
Primary research applications include:
- Lipolysis mechanisms - Understanding fat breakdown pathways
- Lipogenesis inhibition - Studying fat storage prevention
- Adipocyte biology - Effects on fat cell function
- Comparative GH studies - Fragment vs full hormone effects
Obesity Research
The peptide enables focused weight studies:
- Body composition effects - Fat mass changes in models
- Visceral fat targeting - Research on abdominal fat
- Energy balance - Effects on metabolic homeostasis
- Combination approaches - Synergy with other interventions
Metabolic Research
Broader metabolic applications:
- Insulin sensitivity - Studies confirming preserved glucose handling
- Lipid profiles - Effects on circulating lipids
- Thermogenesis - Potential energy expenditure effects
AOD-9604 Peptide Specifications
| Specification | Detail |
|---|---|
| CAS Number | 221231-10-3 |
| Molecular Formula | C78H123N23O23S2 |
| Molecular Weight | 1815.1 g/mol |
| Sequence | Tyr-Leu-Arg-Ile-Val-Gln-Cys-Arg-Ser-Val-Glu-Gly-Ser-Cys-Gly-Phe |
| Purity | ≥99% (HPLC) |
| Appearance | White lyophilised powder |
| Solubility | Freely soluble in water |
| Identity | Confirmed by mass spectrometry |
Reconstitution and Handling
Reconstitution Protocol
- Equilibrate to room temperature before opening
- Add sterile bacteriostatic water slowly along vial wall
- Gently swirl to dissolve - avoid shaking
- Prepare aliquots for longer storage
Storage Recommendations
| Condition | Temperature | Duration |
|---|---|---|
| Lyophilised | -20°C | Up to 24 months |
| Reconstituted | 2-8°C | Up to 3-4 weeks |
| Frozen aliquots | -20°C | Up to 3 months |
Why Choose Peptide Shop?
Guaranteed Purity
- ≥99% purity by HPLC
- Identity confirmation by mass spectrometry
- Comprehensive COA documentation
UK-Based Delivery
- Fast domestic shipping
- Next-day option available
- Temperature-controlled packaging
Ordering Information
| Size | Recommended For |
|---|---|
| 2 mg | Pilot studies |
| 5 mg | Standard research |
Minimum order: £200 | 10% discount on orders over £200
Research Use Statement
This product is sold exclusively for laboratory research purposes. AOD-9604 from Peptide Shop is not intended for human or veterinary use.
Product Specifications
| CAS Number | 221231-10-3 |
|---|---|
| Molecular Weight | 1815.1 g/mol |
| Purity | ≥ 99% |
| Storage | -20°C recommended (research-only) |
| Available Sizes | 10 × 5 mg vials |
| Price Range | £300 per pack |
FAQ
AOD-9604 is used primarily in fat metabolism and lipolysis research. Scientists study its effects on adipocyte function, lipid mobilisation, and metabolic regulation without the IGF-1 elevating effects of full growth hormone.
AOD-9604 is the modified form of HGH Fragment 176-191 with a tyrosine residue added. This modification may enhance stability and activity. Both target the same lipolytic region of growth hormone without affecting blood glucose.
Store lyophilised AOD-9604 at -20°C for optimal long-term stability. Once reconstituted, keep refrigerated at 2-8°C and use within 3-4 weeks. Avoid freeze-thaw cycles.
Our AOD-9604 is ≥99% pure as verified by HPLC analysis. Each batch includes a Certificate of Analysis with purity data, mass spectrometry identity confirmation, and peptide content analysis.
Research indicates AOD-9604 retains lipolytic activity without stimulating IGF-1 production, distinguishing it from full growth hormone. This makes it valuable for studying isolated fat metabolism effects.
Reconstitute AOD-9604 in sterile bacteriostatic water. Add solvent slowly along the vial wall and gently swirl. Common research concentrations are 1-2 mg/mL.
AOD-9604 represents the fat-reducing region of human growth hormone (amino acids 177-191). It stimulates lipolysis and inhibits lipogenesis in adipose tissue without affecting glucose metabolism.
AOD-9604 is available in 2mg and 5mg vials. The 2mg size is ideal for pilot studies while 5mg suits larger research projects.
Customer Reviews (15)
Based on 15 reviews
Dr. Sarah Mitchell • 2024-12-15Verified Purchase
We're studying lipolysis mechanisms and Peptide Shop' AOD-9604 is perfect. Purity is verified and results are consistent with published literature.
Newcastle Fat Metabolism Lab • 2024-12-08Verified Purchase
Switched from an overseas supplier and the quality difference is noticeable. Better activity in our adipocyte assays. Fast UK delivery is a bonus.
Michael Thompson • 2024-12-01Verified Purchase
Easy ordering, quick delivery, excellent quality. AOD-9604 performed as expected in our lipid metabolism studies.
Edinburgh Metabolic Studies • 2024-11-24Verified Purchase
Been ordering AOD-9604 for months. Consistent quality batch to batch is essential for our long-term research. Peptide Shop delivers.
Dr. James Foster • 2024-11-17Verified Purchase
Ran our own HPLC analysis - purity exceeds 99% as stated. Essential for serious fat metabolism research.
Manchester Adipose Lab • 2024-11-10Verified Purchase
After testing several suppliers, Peptide Shop offers the best AOD-9604. Quality, price, and service are all excellent.
Hannah Clarke • 2024-11-03Verified Purchase
Next-day delivery arrived as promised. Product quality excellent. Will continue ordering from Peptide Shop.
Oxford Metabolism Group • 2024-10-27Verified Purchase
Our lipogenesis studies require high-quality peptides. AOD-9604 from Peptide Shop consistently performs well.
Dr. Catherine Moore • 2024-10-20Verified Purchase
Excellent product overall. Only 4 stars as we'd like a 10mg size for larger studies. Quality itself is outstanding.
Glasgow Fat Research • 2024-10-13Verified Purchase
High-quality AOD-9604 with comprehensive documentation. Essential for our comparative fat metabolism studies.
David Williams • 2024-10-06Verified Purchase
First order with Peptide Shop - impressed with professionalism. AOD-9604 quality is exactly as described.
Southampton Adipocyte Lab • 2024-09-29Verified Purchase
Multiple orders over the past year. Quality has been consistently excellent. Our preferred supplier for AOD-9604.
Dr. Robert Hayes • 2024-09-22Verified Purchase
Excellent AOD-9604 for our lipolysis research. Purity verified and documentation is thorough.
Bristol Obesity Research • 2024-09-15Verified Purchase
Premium quality at a fair price. Essential for studying GH fragment effects on fat metabolism.
Emma Richardson • 2024-09-08Verified Purchase
Quick delivery, great quality. The 2mg size is perfect for our pilot experiments.
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