Buy O-304
Buy O-304. AMPK activator for metabolic research. ≥99% purity. Fast UK delivery.
What is O-304?
O-304 is a novel small molecule that directly activates AMPK (AMP-activated protein kinase), the master regulator of cellular energy homeostasis. Unlike indirect activators like metformin, O-304 binds directly to AMPK’s β1 subunit.
Research interest in O-304 stems from its potential applications in metabolic disease, diabetes, and obesity research, where AMPK activation can improve glucose uptake and lipid oxidation.
Peptide Shop supplies research-grade O-304 with guaranteed ≥99% purity.
How Does O-304 Work?
Direct AMPK Activation
- β1 subunit binding - Allosteric activation
- Kinase activation - Phosphorylation cascade
- Energy sensing - Metabolic regulation
Metabolic Effects
- Glucose uptake - GLUT4 translocation
- Fatty acid oxidation - Lipid metabolism
- Mitochondrial biogenesis - Energy production
- Insulin sensitivity - Glucose handling
Downstream Pathways
- ACC inhibition - Fat synthesis reduction
- PGC-1α activation - Mitochondrial genes
- mTOR inhibition - Growth regulation
Research Applications
Diabetes Research
- Glucose metabolism - Uptake mechanisms
- Insulin sensitivity - Resistance models
- Beta cell function - Pancreatic studies
Obesity Research
- Lipid metabolism - Fat oxidation
- Energy expenditure - Thermogenesis
- Appetite regulation - Central effects
Exercise Mimetics
- Metabolic adaptation - Training effects
- Endurance - Performance research
O-304 Specifications
| Specification | Detail |
|---|---|
| CAS Number | 1261289-97-1 |
| Molecular Weight | 319.4 g/mol |
| Purity | ≥99% (HPLC) |
| Appearance | White to off-white powder |
| Solubility | DMSO, ethanol |
Storage
| Condition | Temperature | Duration |
|---|---|---|
| Powder | -20°C | Up to 24 months |
| DMSO stock | -20°C | Up to 6 months |
Ordering Information
| Size | Price |
|---|---|
| 10 mg | From £55 |
| 25 mg | From £120 |
| 50 mg | From £195 |
Minimum order: £200 | 10% discount on orders over £200
Research Use Statement
For laboratory research only. Not intended for human or veterinary use.
Product Specifications
| CAS Number | 1261289-97-1 |
|---|---|
| Molecular Weight | 319.4 g/mol |
| Purity | ≥ 99% |
| Storage | -20°C recommended (research-only) |
| Available Sizes | 3 g powder |
| Price Range | £270 per unit |
FAQ
O-304 is studied as a direct AMPK activator for metabolic research, including glucose metabolism, lipid oxidation, and energy homeostasis.
O-304 directly activates AMPK (AMP-activated protein kinase) by binding to the β1 subunit, enhancing cellular energy regulation.
AMPK is a master metabolic regulator that senses cellular energy status and coordinates anabolic/catabolic processes. It's activated by low energy states.
Store O-304 at -20°C protected from light and moisture. Reconstituted solutions should be used promptly.
Our O-304 is ≥99% pure as verified by HPLC. Each batch includes a Certificate of Analysis.
O-304 directly activates AMPK while metformin works indirectly through mitochondrial inhibition. O-304 is more selective.
Dissolve in DMSO for stock solutions. Dilute in aqueous buffers for working concentrations.
O-304 is available in 10mg, 25mg, and 50mg quantities.
Customer Reviews (10)
Based on 10 reviews
Dr. Jennifer Walsh • 2024-12-06Verified Purchase
O-304 quality is exceptional for our metabolic studies. AMPK activation clearly measurable.
Cambridge Metabolism Lab • 2024-11-29Verified Purchase
Glucose metabolism effects clearly observable. Quality is research-grade.
James Foster • 2024-11-22Verified Purchase
Fast delivery, excellent quality. Energy metabolism research progressing well.
Edinburgh Metabolic Lab • 2024-11-15Verified Purchase
Consistent quality for our AMPK studies.
Dr. Michael Roberts • 2024-11-08Verified Purchase
Purity verification confirms excellent quality.
Manchester Diabetes Lab • 2024-11-01Verified Purchase
Fast delivery, great quality for metabolic studies.
Sophie Williams • 2024-10-25Verified Purchase
Express delivery was prompt. Quality excellent.
Oxford Metabolic Research • 2024-10-18Verified Purchase
Quality is excellent for lipid oxidation research.
Dr. Robert Hayes • 2024-10-11Verified Purchase
Excellent for AMPK pathway studies.
Newcastle Metabolism Lab • 2024-10-04Verified Purchase
Multiple orders, consistently excellent.
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