Buy Tesofensine UK
Buy Tesofensine UK. Triple reuptake inhibitor for weight and neuroscience research. ≥99% purity. Fast UK delivery.
What is Tesofensine?
Tesofensine (NS2330) is a triple monoamine reuptake inhibitor that blocks the presynaptic reuptake of norepinephrine, dopamine, and serotonin. Originally developed for neurodegenerative disease research, tesofensine has become an important tool for studying the neurological basis of appetite regulation and energy homeostasis.
Unlike single-target compounds, tesofensine’s triple mechanism enables researchers to investigate the complex interplay between monoaminergic systems in controlling food intake and metabolic rate. This makes it valuable for understanding the neuropharmacology of obesity and appetite disorders.
Peptide Shop supplies research-grade Tesofensine with guaranteed ≥99% purity, verified through comprehensive HPLC analysis.
How Does Tesofensine Work?
Tesofensine increases synaptic concentrations of three key neurotransmitters:
Norepinephrine Effects
- Sympathetic activation - Increased metabolic rate
- Appetite suppression - Reduced hunger signalling
- Energy expenditure - Enhanced thermogenesis
- Lipolysis promotion - Fat mobilisation effects
Dopamine Effects
- Reward pathway modulation - Altered food reward
- Motivation effects - Changes in food-seeking behaviour
- Satiety enhancement - Earlier meal termination
- Hedonic eating - Reduced pleasure-driven consumption
Serotonin Effects
- Satiety signalling - Enhanced fullness perception
- Mood effects - Emotional eating modulation
- Carbohydrate preference - Altered macronutrient choices
Research Applications
Obesity Research
- Appetite mechanisms - Understanding hunger/satiety
- Energy balance - Metabolic rate studies
- Feeding behaviour - Food choice research
Neuroscience
- Monoamine systems - Reuptake inhibition studies
- Receptor pharmacology - Transporter research
- Behavioural neuroscience - Motivation and reward
Specifications
| Specification | Detail |
|---|---|
| CAS Number | 402856-42-2 |
| Molecular Weight | 382.5 g/mol |
| Purity | ≥99% (HPLC) |
| Appearance | White to off-white powder |
| Solubility | Soluble in DMSO, methanol |
Storage
Store at room temperature, protected from light and moisture.
Ordering Information
| Size | Price |
|---|---|
| 10 mg | From £42 |
| 25 mg | From £95 |
Minimum order: £200 | 10% discount on orders over £200
Research Use Statement
For laboratory research only. Not intended for human or veterinary use.
Product Specifications
| CAS Number | 402856-42-2 |
|---|---|
| Molecular Weight | 382.5 g/mol |
| Purity | ≥ 99% |
| Storage | Room temperature, protected from light |
| Available Sizes | 60 × 0.5 mg caps |
| Price Range | £240 per bottle |
FAQ
Tesofensine is used in neuroscience and obesity research to study triple monoamine reuptake inhibition. It blocks reuptake of norepinephrine, dopamine, and serotonin, enabling research into appetite regulation and energy expenditure mechanisms.
Tesofensine inhibits reuptake of three neurotransmitters (NE, DA, 5-HT) rather than primarily affecting one system. This triple mechanism enables research into complex monoaminergic appetite regulation.
Tesofensine was initially developed as a potential Parkinson's and Alzheimer's disease treatment. Weight loss observed in trials led to obesity research applications.
Store Tesofensine at room temperature, protected from light and moisture. Unlike peptides, it doesn't require cold storage. Keep in a cool, dry place.
Our Tesofensine is ≥99% pure as verified by HPLC analysis. Each batch includes a Certificate of Analysis with purity and identity confirmation.
Tesofensine inhibits presynaptic reuptake of norepinephrine, dopamine, and serotonin, increasing synaptic concentrations of these neurotransmitters to affect appetite, satiety, and energy expenditure.
Tesofensine can be dissolved in DMSO or appropriate organic solvents for in vitro research. Consult literature for specific research application protocols.
Tesofensine is available in 10mg and 25mg sizes for various research scales.
Customer Reviews (12)
Based on 12 reviews
Dr. Michael Roberts • 2024-12-12Verified Purchase
Our monoamine reuptake studies require high-purity compounds. Peptide Shop delivers excellent quality with proper documentation.
Cambridge Neuropharmacology • 2024-12-05Verified Purchase
Tesofensine purity is exceptional. Results in our receptor binding assays are highly reproducible.
James Foster • 2024-11-28Verified Purchase
Fast delivery, excellent quality. Perfect for our appetite regulation research.
Edinburgh Neuroscience Lab • 2024-11-21Verified Purchase
Consistent quality for our monoamine studies. Peptide Shop is our preferred supplier.
Dr. Sarah Mitchell • 2024-11-14Verified Purchase
Verified purity exceeds claims. Essential for serious neuropharmacology research.
Manchester Obesity Research • 2024-11-07Verified Purchase
Fast delivery, great quality. The 25mg size lasts well for our studies.
Sophie Williams • 2024-10-31Verified Purchase
Express delivery was prompt. Product quality excellent for our research.
Oxford Weight Research • 2024-10-24Verified Purchase
Quality is excellent. Would give 5 stars with larger size options.
Dr. Robert Hayes • 2024-10-17Verified Purchase
Excellent for studying triple reuptake effects. Quality and documentation meet our requirements.
Newcastle Appetite Lab • 2024-10-10Verified Purchase
Multiple orders, consistently excellent. Essential for our neurotransmitter research.
Michael Thompson • 2024-10-03Verified Purchase
Easy ordering, quick delivery. Tesofensine quality is exactly as described.
Glasgow Neuropharm Lab • 2024-09-26Verified Purchase
High-quality compound with proper documentation. Highly recommended.
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